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The Pill That Could

The first targeted cancer drug

The decades-long story of Gleevec — from the Philadelphia chromosome and a single rogue gene to the first pill that turned a fatal leukemia into a manageable disease — including the long argument to make it, the resistance that followed, and what “cure” really means.

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13chapters
46pages
51kwords

Contents

  1. Prologue: A Patient in Portland
  2. Philadelphia, 1960
  3. The Translocation
  4. BCR-ABL
  5. The Compound
  6. The Long Argument
  7. First in Human
  8. Approval
  9. A Different Cancer
  10. Resistance
  11. What Cure Means
  12. The Generalization Problem
  13. The Patients Who Waited